Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Inflammation
ADR ID BADD_A05823
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.05      Inflammations
08.01.05.007      Inflammation
Description A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code 10061218
MeSH ID D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Interleukin-1 alphaP01583T16340
Interleukin-10P29456Not Available
Interleukin-6P05231T32578
Interleukin-8P10145T22658
Nuclear receptor subfamily 4 group A member 3Q92570T93949
Retinol-binding protein 1P09455Not Available
Tumor necrosis factorP01375T20178
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01150Indinavir--
BADD_D01158Ingenol mebutate0.007669%
BADD_D01160Insulin aspart--
BADD_D01162Insulin detemir--
BADD_D01163Insulin glargine--
BADD_D01166Interferon alfa-2a--
BADD_D01167Interferon alfa-2b--
BADD_D01182Iopromide--
BADD_D01191Ipratropium--
BADD_D01194Irbesartan0.000603%
BADD_D01197Iron--
BADD_D01198Iron dextran--
BADD_D01213Isotretinoin--
BADD_D01235Kinetin--
BADD_D01242Lamivudine--
BADD_D01243Lamotrigine0.001933%
BADD_D01244Lanreotide acetate--
BADD_D01245Lansoprazole--
BADD_D01250Lasofoxifene--
BADD_D01251Latanoprost0.000338%
BADD_D01252Leflunomide0.006197%
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib--
BADD_D01257Letrozole0.001846%
BADD_D01260Leuprolide acetate--
BADD_D01261Leuprolide monoacetate--
BADD_D01265Levetiracetam--
BADD_D01275Levofloxacin--
BADD_D01281Levonorgestrel--
BADD_D01285Levothyroxine0.000092%
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